Vol. 1, Issue 1, Part A (2024)

Antimicrobial resistance (AMR) poses a global threat to public health, jeopardizing the efficacy of existing antibiotics and requiring innovative solutions. The development of novel antimicrobial agents has emerged as a critical strategy to address multidrug-resistant (MDR) pathogens. This article evaluates the efficacy and safety of these agents in clinical settings, focusing on their mechanisms of action, evidence from clinical trials, and real-world applications. The paper also explores challenges such as resistance emergence, accessibility issues, and regulatory hurdles. Supported by recent studies, comparative analyses, and real-world data, the findings underscore the need for integrated strategies to optimize the development and deployment of novel antimicrobial agents.